The North American cruise sector has been one of the hardest-hit markets by the COVID19 pandemic. With the cruise fleet largely in lay-up and major tourist destination ports impacted, the upscaled vaccination programs in the US and Canada are now beginning to offer hope for a restart to the cruise and passenger vessel business. What will the startup look like, and what will ports need to do to play their role in the sustainable reemergence and prosperity of cruise voyaging, both ashore and at sea?